Tuesday, December 11, 2018

Allotrope Medical’s Proprietary Electrical Stimulation Technology


For the last 30 years, SP Investment Fund and its affiliates have successfully acquired, developed and/or redeveloped affordable housing properties that are restricted to occupancy by and affordable to low and very low-income seniors, families and disabled individuals. SP Investment Fund has also broadened the scope of its investments to include health sciences and biotechnology startups like Allotrope Medical.

Backed by Y-Combinator, Allotrope Medical is a Houston-based medical-device company that aims to minimize injuries to the ureter during surgery. The company developed a low-powered electrical-stimulation technology to generate visible contractions in the ureter and other smooth-muscle structures when a patient undergoes invasive or robotic surgery. Allotrope has customized electrodes that are suitable to endoscopic, laparoscopic, and robotic surgical procedures.

Additionally, Allotrope’s tissue-stimulation applications can be attached to a medicinal capsule as an ingestible device that can monitor and stimulate digestive movements in the gastrointestinal system.

Allotrope is currently conducting an active clinical trial in Dallas and getting ready to put its product on the market by the end of 2019.

Friday, December 7, 2018

Coral Genomics Designs Advance Drug Response Prediction System


Based in California, SP Investment Fund focuses on socially positive real estate and emerging technology investments. In addition to being an active investor, developer and renovator of affordable housing for low and very low income seniors, families and disabled individuals, SP Investment Fund has also made significant investments in emerging health sciences and biotechnology companies, including Coral Genomics.

Based in San Carlos, California, Coral Genomics is a biotech startup that has designed a proprietary platform to accelerate drug development and deployment by performing experiments on a vast database of cells and measuring and finding correlations with DNA and RNA expressions. Without Coral Genomic’s technology, such big data analysis has heretofore not been economically viable. Coral Genomics’ drug-response prediction system is a three-step process, which includes targeting variability, comparing it to other patients, and recommending treatment strategies.

Coral utilizes the patient’s genetic profile and measures RNA expression to determine how likely the cells within the body will react to a specific drug. The profile consists of characteristics unique to the DNA of an individual or population, derived from the analysis of small samples of body tissues or fluids. As the patient’s susceptibility to a particular drug becomes clear, Coral can begin to perform experiments that will reduce variation across patients.

Currently in its first year, Coral Genomics believes that this new platform will improve the efficiency of clinical trials and healthcare delivery.

Monday, December 3, 2018

C16 Biosciences Develops a Sustainable Alternative to Palm Oil


Based in California, SP Investment Fund is a private investment company that primarily invests in socially positive investments. SP Investment Fund’s core business has been investing in, developing and/or renovating government-subsidized housing for low and very low income families, seniors and/or disabled individuals. In 2014, SP Investment Fund expanded its focus to include emerging-technology businesses whose businesses will have significant social impacts. One such company that SP has invested in is C16 Biosciences. C16 Biosciences has also received funding from YCombinator. 

C16 Biosciences is a Boston startup that concentrates on developing a sustainable alternative to producing palm oil through biotechnology, by bioengineering yeast to produce palm oil and related compounds. Palm oil is a commodity that has huge global demand and is used widely in food, skin-care, and clothing items. The palm oil industry is currently a $61 billion industry and growing rapidly. 

The sustainability problem is that palm oil can only be harvested in the tropics, and increasing palm oil production is resulting in rain forest deforestation. The resulting deforestation is a huge contributor to global warming, and also is endangering habitats and wildlife. Unfortunately, industry has continued to demand palm oil because there are no good substitutes in nature.